By Steven Martin
NEW YORK instances BESTSELLER
A well known authority at the mystery global of opium recounts his descent into ruinous obsession with one of many world’s oldest and such a lot seductive medications, during this harrowing memoir of dependancy and recovery.
A natural-born collector with a nostril for unique event, San Diego–born Steven Martin his bliss to Southeast Asia, the place he chanced on paintings as a contract journalist. whereas studying an editorial concerning the vanishing tradition of opium smoking, he used to be encouraged to start accumulating infrequent nineteenth-century opium-smoking gear. through the years, he accrued a worthwhile collection of beautiful pipes, old lamps, and different opium-related accessories—and all started placing all of it to take advantage of by means of smoking an exceptionally powerful type of the drug referred to as chandu. yet what began as leisure use grew right into a thirty-pipe-a-day behavior that ate up Martin’s each waking hour, left him incapable of labor, and exacted a frightful actual and monetary toll. In passages that would ship a sit back up the backbone of an individual who has ever lived within the shadow of substance abuse, Martin chronicles his efforts to manage after which triumph over his addiction—from quitting chilly turkey to taking “the healing” at a Buddhist monastery within the Thai countryside.
immediately a strong own tale and a desirable historic survey, Opium Fiend brims with anecdotes and lore surrounding the drug that a few have known as the methamphetamine of the nineteenth-century. It recollects the heyday of opium smoking within the usa and Europe and takes us contained in the befogged opium dens of China, Thailand, Vietnam, and Laos. The drug’s beguiling results are defined in bright detail—as are the excruciating pains of withdrawal—and there are intoxicating stories of pipes shared with an eclectic selection of opium aficionados, from Dutch dilettantes to hard-core addicts to world-weary overseas correspondents.
A compelling story of 1 man’s transformation from revered student to hapless drug slave, Opium Fiend places us lower than opium’s spell along its protagonist, permitting modern readers to event anew the insidious attract of a diabolical vice that the area has all yet forgotten.
By David E. Nichols
Released in Pharmacology & Therapeutics one zero one (2004) 131– 181
"Hallucinogens (psychedelics) are psychoactive ingredients that powerfully modify notion, temper, and a bunch of cognitive techniques. they're thought of physiologically secure and don't produce dependence or habit. Their foundation predates written historical past, and so they have been hired via early cultures in various sociocultural and formality contexts. within the Fifties, after the almost contemporaneous discovery of either serotonin (5-HT) and lysergic acid diethylamide (LSD-25), early mind learn concentrated intensely at the risk that LSD or different hallucinogens had a serotonergic foundation of motion and bolstered the concept 5-HT used to be a massive neurotransmitter in mind. those rules have been ultimately confirmed, and this present day it's believed that hallucinogens stimulate 5-HT2A receptors, specifically these expressed on neocortical pyramidal cells. Activation of 5-HT2A receptors additionally ends up in elevated cortical glutamate degrees most likely through a presynaptic receptor-mediated unencumber from thalamic afferents. those findings have ended in comparisons of the results of classical hallucinogens with yes elements of acute psychosis and to a spotlight on thalamocortical interactions as key to figuring out either the motion of those ingredients and the neuroanatomical websites excited about altered states of cognizance (ASC). In vivo mind imaging in people utilizing [18F]fluorodeoxyglucose has proven that hallucinogens elevate prefrontal cortical metabolism, and correlations were built among job in particular mind components and mental components of the ASC produced through hallucinogens. The 5-HT2A receptor truly performs an important position in cognitive processing, together with operating reminiscence, and ligands for this receptor might be tremendous worthy instruments for destiny cognitive neuroscience study. furthermore, it seems that completely attainable that software should still emerge for using hallucinogens in treating alcoholism, substance abuse, and sure psychiatric disorders."
By Daniel Pinchbeck
A extraordinary paintings of non-public travelogue and cultural feedback that levels from the primitive to the postmodern in a quest for the promise and that means of the psychedelic experience.
While psychedelics of all kinds are demonized in the US at the present time, the visionary compounds present in vegetation are the non secular sacraments of tribal cultures world wide. From the iboga of the Bwiti in Gabon, to the Mazatecs of Mexico, those crops are sacred simply because they wake up the brain to different degrees of awareness--to a holographic imaginative and prescient of the universe.
Breaking Open the Head is a passionate, multilayered, and occasionally rashly own inquiry into this deep department. On one point, Daniel Pinchbeck tells the tale of the encounters among the fashionable awareness of the West and those sacramental elements, together with such thinkers as Allen Ginsberg, Antonin Artaud, Walter Benjamin, and Terence McKenna, and a brand new underground of present-day ethnobotanists, chemists, psychonauts, and philosophers. it's also a scrupulous recording of the author's wide-ranging research with those outlaw compounds, together with a thirty-hour tribal initiation in West Africa; an all-night stumble upon with the grasp shamans of the South American rain wooded area; and a record from a psychedelic utopia within the Black Rock wasteland that's the Burning guy Festival.
Breaking Open the Head is courageous participatory journalism at its top, a vibrant account of psychic and highbrow reviews that opened doorways within the wall of Western rationalism and accomplished Daniel Pinchbeck's own transformation from a jaded long island journalist to shamanic start up and thankful citizen of the cosmos.
From the Hardcover edition.
By Ann Beattie
The now-classic, completely detailed voice of Ann Beattie is so dry it throws off sparks, her eye endowed with the emotional an identical of X-ray imaginative and prescient. Her characters are younger women and men getting to know what it skill to be a grown-up in a rustic that promised them they'd remain younger endlessly. And the following, in shapely, penetrating tales, Beattie confirms why she is among the most generally imitated -- but without doubt inimitable -- literary stylists of her generation.
In The Burning residence, Beattie's characters move from dealing medicinal drugs to caring for a bereaved buddy. They watch their marriages fail no longer with a bang yet with a wisecrack. And later on, they could locate themselves buying and selling confidences with their spouses' new enthusiasts. The Burning condominium proves that Beattie has no peer by way of revealing the hidden shapes of our relations, or the depths of tenderness, grief, and anger that lie underneath the surfaces of our day-by-day lives.
By Sally Denton
Whilst Kentucky Blueblood Drew Thornton parachuted to his dying in September 1985 sporting millions in funds and a hundred and fifty kilos of cocaine the ugly finish of his startling existence blew open a scandal that reached to the main mystery circles of the U.S. executive. the tale of Thornton and the corporate he served, and the lone heroic struggle of nation Policeman Ralph Ross opposed to a world net of corruption is without doubt one of the such a lot portentous stories of the twentieth century.
By Elizabeth Connell Henderson
At least one among each 4 humans in the United States has had a few event with addiction--either individually or via a loved one. habit and its effects expense billions of greenbacks every year in direct scientific expenses, misplaced productiveness, injuries, crime, and corruption. but as a disorder, habit remains to be principally misunderstood.
Starting with the query "what is addiction?" Elizabeth Connell Henderson takes the reader in the course of the many aspects of this illness. She examines the consequences of addictive ingredients at the mind and studies all the significant periods of gear. within the improvement of habit, she appears to be like on the genetic, social, and mental factors.
Henderson exhibits the results of dependancy at the kinfolk and courses the reader on a trip throughout the process the ailment and the method of restoration. extra chapters care for the issues linked to twin diagnosis--when dependancy is observed via different psychiatric health problems. additionally chapters hide behavioral addictions resembling compulsive overeating, pathological playing, and sexual addiction.
Covered are: Who turns into addicted and why? What are the homes of the key addictive medicines? what's the process habit? How does habit have an effect on the relations? What constitutes restoration? What are the present tendencies in learn? What agencies can be found for support and the way are they contacted?
For the addict in restoration and for the relatives of the troubled, Understanding Addiction presents an important info to demystify this sickness and supply transparent tips towards restoration. For human source employees, lawyers, social staff, nurses, corrections officials, institution counselors, and lecturers, the booklet presents a framework of functional info for supporting person victims and dealing with their precise struggles.
By Richard J. Miller
"Morphine," writes Richard J. Miller, "is the main major chemical substance mankind has ever encountered." So historical that continues to be of poppies were present in Neolithic tombs, it's the most suitable drug ever found for treating discomfort. "Whatever advances are made in medicine," Miller provides, "nothing might rather be extra very important than that." And but, in terms of mind-altering elements, morphine is simply a cc or in an unlimited river that flows via human civilization, ranging LSD to a morning cup of tea.
In DRUGGED, Miller takes readers on an eye-opening travel of psychotropic medicinal drugs, describing a few of the types, how they have been found and constructed, and the way they've got performed a number of roles in nearly each tradition. The significant scope of chemical compounds that go the blood-brain barrier boggle the very mind they achieve: hashish and cocaine, antipsychotics and antidepressants, alcohol, amphetamines, and Ecstasy-and even more. Literate and wide-ranging, Miller weaves jointly technological know-how and heritage, telling the tale of the undercover robbery of 20,000 tea vegetation from China by way of a British secret agent, for instance, the ecu discovery of espresso and chocolate, and the way James Wolfgang von Goethe, the well-known guy of letters, first remoted the alkaloid we now be aware of as caffeine. Miller explains what scientists know-and don't-about the effect of every drug at the mind, right down to the main points of neurotransmitters and their receptors. He clarifies the variations among morphine and heroin, mescaline and LSD, and different comparable ingredients. Drugged brims with surprises, revealing the truth that antidepressant medicinal drugs developed from the rocket gasoline that shot V2 rockets into London in the course of global conflict II, highlighting the position of hallucinogens within the background of faith, and asking even if Prozac might help depressed cats.
Entertaining and authoritative, Drugged is a really interesting ebook.
By Brigid M. Kane
A good soreness reliever from the opiate type of gear, codeine is frequently prescribed to regard individuals with critical respiration infections or these convalescing from dental or different surgical procedure. it's also prescribed as a cough suppressant. yet simply because this alkaloid narcotic may be effortless to acquire in quite a few varieties - within the U.S. and overseas - it really is usually abused through humans looking its euphoric results. This new ebook offers scholars very important and independent information regarding this addictive substance and the way it impacts either the brain and physique. easy evidence mixed with full-color images and illustrations, a thesaurus, sidebars, and different gains makes "Codeine" an instructive advisor to the strong painkiller usually diverted for abuse.
By Trish Regan
- A attention-grabbing research into the internal workings of present day exploding American marijuana industry
- Based on broad learn and interviews via Trish Regan, whose Emmy nominated documentary Marijuana, Inc. attracted extra audience than any documentary in CNBC's history
- Regan examines all facets of this new tradition. She finds how small time growers get their begin, make (or lose) a fortune, fight with violence, try and stay alongside of regularly altering legislation and rules all whereas jogging an more and more wonderful line with the Feds
- Regan experiences at the present and capability impression of legalized marijuana on neighborhood economies, uncovers the hyperlink among marijuana and violent Mexican cartels, questions even if decriminalization might paintings on a countrywide scale, because it has in Portugal when you consider that 2001
As the decriminalization and legalization debates assemble steam, Joint Ventures hands you with the evidence on either side of the issue.